Description
Product Name: | Nanodisc Human NMDE4-Strep Protein |
SKU: | HDFP1459 |
Size: | 10μg |
Target: | NMDE4 |
Tag: | C-Flag&Strep Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | DEE46, EB11, EIEE46, GluN2D, NMDAR2D, NR2D |
Protein Families: | Ion Channels: Glutamate Receptors. |
Protein Description: | Human NMDE4-Strep full length protein-synthetic nanodisc |
Molecular Weight: | The human full length NMDE4-Strep protein has a MW of 143.8 kDa |
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]
Uniprot ID: | O15399 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |