Description
| Product Name: | Nanodisc Human PLA2R1-Strep Protein |
| SKU: | HDFP882 |
| Size: | 10μg |
| Target: | PLA2R1 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R |
| Protein Families: | Druggable Genome, Transmembrane. |
| Protein Description: | Human PLA2R1-Strep full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length PLA2R1-Strep protein has a MW of 168.6 kDa |
This protein is a phospholipase A2 receptor. The protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Uniprot ID: | Q13018 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
