The CD275 Polyclonal Antibody (CAB24440) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been extensively validated for use in Western blot applications. CD275, also known as inducible T-cell co-stimulator ligand (ICOSL), is essential for the activation and regulation of T-cells in the immune response. Its function in co-stimulating T-cell proliferation and cytokine production makes it a crucial target for studies in immunology, cancer research, and autoimmune diseases.
This antibody is validated for use in WB applications and has demonstrated reactivity against Mouse samples.
Product Name:
CD275 Polyclonal Antibody
SKU:
CAB24440
Size:
100μL
Reactivity:
Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Enables identical protein binding activity. Predicted to be involved in T cell receptor signaling pathway and positive regulation of interleukin-4 production. Located in cytoplasmic ribonucleoprotein granule and plasma membrane.
Purification Method
Affinity purification
Gene ID
23308
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse kidney, using CD275 Rabbit pAb (CAB24440) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.