The IFNA1 Antibody (CAB0285) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is produced in rabbits and has high reactivity with human samples, making it ideal for use in Western blot applications. By specifically binding to IFNA1, researchers can easily detect and analyze this important protein in various cell types.IFNA1 is a potent cytokine that is involved in antiviral immune responses and has shown promise in cancer therapy due to its ability to inhibit tumor growth.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
IFNA1 Antibody
SKU:
CAB0285
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Raji, Recombinant Human Interferon alpha 1 (IFN-α1) Protein
Cellular Localization:
Secreted.
Calculated MW:
22kDa
Observed MW:
18kDa/22kDa
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.
Purification Method
Affinity purification
Gene ID
3439
RRID
AB_2757097
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of Recombinant Human IFN-alpha 1/13(Q114A) Protein (RP00011), using Interferon alpha 1 (IFN-α1) Rabbit pAb (CAB0285) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 10ng/5ng per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Western blot analysis of lysates from Raji cells, using Interferon alpha 1 (IFN-α1) Rabbit pAb (CAB0285) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
