Description
IFNA14 Antibody (PACO27525)
The IFNA14 Monoclonal Antibody (PACO27525) is a powerful tool for researchers studying the interferon family, particularly IFNA14, a type I interferon with antiviral and immunomodulatory properties. This antibody, produced using hybridoma technology, exhibits high specificity and sensitivity for detecting IFNA14 in human samples, making it a valuable asset in immunoassays and cell studies.IFNA14 is a key player in the innate immune response, activating antiviral defense mechanisms and enhancing immune cell functions.
Its role in immune regulation and antiviral activity makes it a promising target for investigating viral infections, autoimmune diseases, and cancer. By utilizing the IFNA14 Monoclonal Antibody, researchers can delve into the mechanisms underlying IFNA14's functions and explore its potential as a therapeutic target in various disease contexts.
| Antibody Name: | IFNA14 Antibody (PACO27525) |
| Antibody SKU: | PACO27525 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Interferon alpha-14 protein (24-189AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: IFNA14 antibody at 2µg/ml Lane 1: A549 whole cell lysate Lane 2: Mouse heart tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 23 kDa Observed band size: 23 kDa . |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO27525 at dilution of 1:100. |
| Background: | Produced by macrophages, IFN-α have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
| Synonyms: | Interferon alpha-14 (IFN-alpha-14) (Interferon alpha-H) (LeIF H) (Interferon lambda-2-H), IFNA14 |
| UniProt Protein Function: | IFNA14: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Membrane protein, integral Chromosomal Location of Human Ortholog: 9p22 Cellular Component: extracellular space; extracellular region Molecular Function:hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding; cytokine activity Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; B cell differentiation; natural killer cell activation during immune response; innate immune response; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein |
| UniProt Code: | P01570 |
| NCBI GenInfo Identifier: | 170763491 |
| NCBI Gene ID: | 3448 |
| NCBI Accession: | NP_002163.2 |
| UniProt Secondary Accession: | P01570,P01566, P05014, P01567, |
| UniProt Related Accession: | P01570 |
| Molecular Weight: | 22,063 Da |
| NCBI Full Name: | interferon alpha-14 |
| NCBI Synonym Full Names: | interferon, alpha 14 |
| NCBI Official Symbol: | IFNA14Â Â |
| NCBI Official Synonym Symbols: | LEIF2H; IFN-alphaHÂ Â |
| NCBI Protein Information: | interferon alpha-14; IFN-alpha-14; interferon alpha-H; interferon lambda-2-H; leIF H |
| UniProt Protein Name: | Interferon alpha-14 |
| UniProt Synonym Protein Names: | Interferon alpha-H; LeIF H; Interferon lambda-2-H |
| UniProt Gene Name: | IFNA14Â Â |
| UniProt Entry Name: | IFN14_HUMAN |
