The IFNGR2 Antibody (CAB14221) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the IFNGR2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it well-suited for investigations in immunology and cancer research.IFNGR2 plays a crucial role in mediating the effects of interferon gamma, a potent immune regulator involved in antiviral defense, anti-tumor immunity, and autoimmune responses.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
IFNGR2 Antibody
SKU:
CAB14221
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
AF-1, IFGR2, IMD28, IFNGT1, IFNGR2
Positive Sample:
A-549, HepG2, Rat heart
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
38kDa
Observed MW:
38kDa
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
Purification Method
Affinity purification
Gene ID
3460
RRID
AB_2761082
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using IFNGR2 Rabbit pAb (CAB14221) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
