The IFT22 Antibody (PAC040594) is a high-quality research tool designed for the detection and analysis of the IFT22 protein, a key component of the intraflagellar transport (IFT) complex. This rabbit polyclonal antibody is highly reactive with human samples and has been validated for use in various applications, including Western blotting.The IFT22 protein is essential for the proper functioning of cilia, cellular structures involved in various biological processes such as signal transduction and cell motility. Dysregulation of IFT22 has been implicated in ciliopathies and other genetic disorders.
This antibody enables researchers to study the expression and localization of IFT22 in different cell types, providing valuable insights into ciliary function and associated disease mechanisms.By targeting IFT22, researchers can advance their understanding of ciliary biology and its role in human health and disease. This antibody is an invaluable tool for studies in cell biology, developmental biology, and genetic disorders related to cilia dysfunction.
Antibody Name:
IFT22 Antibody (PACO40594)
Antibody SKU:
PACO40594
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Intraflagellar transport protein 22 homolog protein (1-185AA)
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO40594 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human heart tissue using PACO40594 at dilution of 1:100.
Background:
Small GTPase-like component of the intraflagellar transport (IFT) complex B.
Synonyms:
Intraflagellar transport protein 22 homolog (Rab-like protein 5), IFT22, RABL5
UniProt Protein Function:
RABL5: Belongs to the small GTPase superfamily. Rab family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: G protein; G protein, monomeric; G protein, monomeric, RabChromosomal Location of Human Ortholog: 7q22.1Cellular Component: centrosomeMolecular Function: GTP bindingBiological Process: organelle organization and biogenesis; small GTPase mediated signal transduction
