The IFT88 Monoclonal Antibody (CAB22622) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated from hybridoma cells, is highly specific for IFT88 and is validated for use in various applications, including immunofluorescence and immunoprecipitation.IFT88, known as intraflagellar transport protein 88, plays a crucial role in ciliary assembly and maintenance, mediating the transport of proteins within the cilium. Dysregulation of IFT88 has been linked to ciliopathies, genetic disorders affecting cilia function, as well as various developmental abnormalities and diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
IFT88 Monoclonal Antibody
SKU:
CAB22622
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC57206
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
This gene encodes a member of the tetratrico peptide repeat (TPR) family. The encoded protein is involved in cilium biogenesis. Mutations of a similar gene in mouse can cause polycystic kidney disease. Several transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method
Affinity purification
Gene ID
8100
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using IFT88 Rabbit mAb (CAB22622) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
