The IGFBP2 Antibody (CAB0403) is a high-quality antibody developed for reliable detection and analysis of target proteins. IGFBP2 is a member of the IGFBP family, known for its role in regulating the activity of insulin-like growth factors. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.IGFBP2 is involved in various biological processes, including cell growth, differentiation, and metabolism. Its dysregulation has been linked to several diseases, such as cancer, diabetes, and cardiovascular disorders, making it a key target for research in these areas.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
IGFBP2 Antibody
SKU:
CAB0403
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
IBP2, IGF-BP53, IGFBP2
Positive Sample:
LO2, HeLa, SW480
Cellular Localization:
Secreted.
Calculated MW:
35kDa
Observed MW:
37kDa
The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
Purification Method
Affinity purification
Gene ID
3485
RRID
AB_2757174
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using IGFBP2 Rabbit pAb (CAB0403) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 30s.
