The IQCJ Polyclonal Antibody (PAC020403) is a valuable tool for researchers studying IQCJ, a protein involved in cell proliferation and differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including immunohistochemistry and flow cytometry.IQCJ is known to play a role in the regulation of cell growth and development, making it a potential target for investigating conditions such as cancer and developmental disorders.
By targeting IQCJ, researchers can gain insights into the molecular mechanisms underlying these diseases and potentially identify new therapeutic strategies.Overall, the IQCJ Polyclonal Antibody is a reliable reagent for studying the function of IQCJ in different biological contexts, offering valuable information for researchers interested in unraveling the complexities of cellular processes and disease pathways.
Antibody Name:
IQCJ Antibody (PACO20403)
Antibody SKU:
PACO20403
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human IQCJ
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20403(IQCJ Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20403(IQCJ Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
IQCJ (IQ domain-containing protein J) is a 159 amino acid, protein that contains one IQ domain. Existing as four alternatively spliced isoforms, the gene encoding IQCJ maps to human chromosome 3q25.32. Chromosome 3 houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.
Synonyms:
IQ motif containing J
UniProt Protein Function:
IQCJ: 5 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3q25.32
