The ITGAD Antibody (PAC013395) is a polyclonal antibody designed for research involving ITGAD, a cell surface molecule that plays a key role in regulating immune responses. This antibody, produced in rabbits, is specifically reactive with human samples and has been validated for use in Western blot applications. By binding to the ITGAD protein, this antibody allows for the detection and analysis of ITGAD in various cell types, making it an ideal tool for studies in immunology and cancer research.
ITGAD, also known as integrin alpha-D, is involved in immune cell adhesion and migration, making it a significant player in the immune response. It is believed to have implications in various diseases including cancer, autoimmune disorders, and chronic inflammatory conditions. By further understanding the role of ITGAD in immune regulation, researchers can potentially develop new therapies that target or modulate immune responses in these disease contexts.
ITGAD: Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood- borne pathogens, particulate matter, and senescent erythrocytes from the blood. Belongs to the integrin alpha chain family.Protein type: Membrane protein, integral; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 16p11.2Cellular Component: cell surface; plasma membrane; integrin complexMolecular Function: metal ion bindingBiological Process: integrin-mediated signaling pathway; heterotypic cell-cell adhesion; extracellular matrix organization and biogenesis; activated T cell proliferation; immune response
