The ITPRIP Antibody (CAB11725) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, has high specificity for human samples and is suitable for use in Western blot applications. By binding to the ITPRIP protein, researchers can accurately detect and analyze its expression in various cell types, making it an ideal choice for studies in cell biology and cancer research.ITPRIP, also known as inositol 1,4,5-trisphosphate receptor-interacting protein, plays a crucial role in mediating calcium release from intracellular stores and regulating cell survival pathways.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
ITPRIP Antibody
SKU:
CAB11725
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
DANGER, KIAA1754, bA127L20, bA127L20.2, ITPRIP
Positive Sample:
U-87MG, HeLa, A-549
Cellular Localization:
Cell Membrane.
Calculated MW:
62kDa
Observed MW:
62kDa
This gene encodes a membrane-associated protein that binds the inositol 1,4,5-trisphosphate receptor (ITPR). The encoded protein enhances the sensitivity of ITPR to intracellular calcium signaling. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
85450
RRID
AB_2758719
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ITPRIP Rabbit pAb (CAB11725) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
