The JAM2 Antibody (CAB9978) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through the immunization of rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.JAM2, also known as Junctional Adhesion Molecule 2, plays a crucial role in regulating the movement of immune cells within tissues and facilitating their interactions with other cells. By binding specifically to JAM2, this polyclonal antibody enables the detection and analysis of this protein in various cell types, providing insight into its function in immune responses and inflammatory processes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
JAM2 Antibody
SKU:
CAB9978
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Cell Junction, Cell Membrane, Single-Pass Type I Membrane Protein, Tight Junction.
Calculated MW:
33kDa
Observed MW:
36kDa
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.
Purification Method
Affinity purification
Gene ID
58494
RRID
AB_2770026
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using JAM2 Rabbit pAb (CAB9978) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Western blot analysis of various lysates using JAM2 Rabbit pAb (CAB9978) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
