Description
KCND2 Antibody (CAB6203)
The KCND2 Antibody (CAB6203) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the KCND2 protein, this antibody allows for the precise detection and analysis of KCND2 expression in a variety of cell types, making it an invaluable resource for studies in neuroscience and neurology.KCND2, also known as Kv4.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
| Product Name: | KCND2 Antibody |
| SKU: | CAB6203 |
| Size: | 20μL, 100μL |
| Reactivity: | Mouse |
| Conjugate: | Unconjugated |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. | ||||
| Sequence: | ESCM EVAT VNRP SSHS PSLS SQQG VTST CCSR RHKK TFRI PNAN VSGS HQGS IQEL STIQ IRCV ERTP LSNS RSSL NAKM EECV KLNC EQPY VTTA IISI PTPP VTTP EGDD RPES PEYS GGNI VRVS AL | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
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| Synonyms: | RK5, KV4.2, KCND2 |
| Positive Sample: | Mouse heart |
| Cellular Localization: | Cell Junction, Cell Membrane, Cell Projection, Multi-Pass Membrane Protein, Perikaryon, Dendrite, Dendritic Spine, Postsynaptic Cell Membrane, Synapse. |
| Calculated MW: | 71kDa |
| Observed MW: | 70kDa |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.
| Purification Method | Affinity purification |
| Gene ID | 3751 |
| RRID | AB_2766813 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
 | Western blot analysis of lysates from Mouse heart, using KCND2 Rabbit pAb (CAB6203) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s. |
