The KCNF1 Polyclonal Antibody (PACO05967) is a valuable tool for researchers studying the KCNF1 gene, which encodes for a potassium channel protein involved in neuronal excitability and signaling. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in various immunological techniques such as Western blotting.KCNF1 plays a crucial role in regulating potassium ion flow across cell membranes, thereby influencing neuronal function and communication. Dysregulation of KCNF1 has been associated with neurological disorders such as epilepsy and intellectual disabilities.
By using the KCNF1 Polyclonal Antibody, researchers can study the expression and localization of the KCNF1 protein in different cell types, advancing our understanding of its role in neuronal physiology and pathophysiology.With its high specificity and validated performance in Western blot applications, the KCNF1 Polyclonal Antibody is a reliable tool for investigating the function and implications of the KCNF1 gene in neurological research. Its use can lead to new insights into the molecular mechanisms underlying neurological disorders and potential therapeutic strategies for targeting KCNF1-related pathways.
Antibody Name:
KCNF1 Antibody (PACO05967)
Antibody SKU:
PACO05967
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:5000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the Internal region of human KCNF1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
KCNF1; Potassium voltage-gated channel subfamily F member 1; Voltage-gated potassium channel subunit Kv5.1; kH1
UniProt Protein Function:
Kv5.1: Putative voltage-gated potassium channel. Belongs to the potassium channel family. F (TC 1.A.1.2) subfamily. Kv5.1/KCNF1 sub-subfamily.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 2p25Cellular Component: integral to membrane; plasma membraneMolecular Function: delayed rectifier potassium channel activity; potassium channel activityBiological Process: potassium ion transport
UniProt Protein Details:
NCBI Summary:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008]
