The KCNF1 Polyclonal Antibody (PACO10051) is a valuable tool for researchers studying the potassium channel, KCNF1. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the KCNF1 protein, this antibody enables the detection and analysis of KCNF1 in various cell types, making it ideal for research in the fields of neuroscience and cardiovascular biology.KCNF1 is a potassium channel that plays an important role in regulating membrane potential and neuronal excitability. Dysregulation of KCNF1 has been linked to neurological disorders such as epilepsy and Parkinson's disease, as well as cardiovascular conditions like arrhythmias.
By studying KCNF1 and its function, researchers can gain insight into the mechanisms underlying these diseases and potentially identify new therapeutic targets.Overall, the KCNF1 Polyclonal Antibody is a valuable tool for researchers interested in studying the role of KCNF1 in health and disease. Its specificity and reliability make it a trusted reagent for Western blot experiments, allowing for accurate and reproducible results in a variety of research settings.
potassium voltage-gated channel, subfamily F, member 1;KCNF1;IK8;KCNF;KV5.1;MGC33316;kH1 ;
UniProt Protein Function:
Kv5.1: Putative voltage-gated potassium channel. Belongs to the potassium channel family. F (TC 1.A.1.2) subfamily. Kv5.1/KCNF1 sub-subfamily.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 2p25Cellular Component: integral to membrane; plasma membraneMolecular Function: delayed rectifier potassium channel activity; potassium channel activityBiological Process: potassium ion transport
UniProt Protein Details:
NCBI Summary:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008]
