The KCNH6 Antibody (CAB15522) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the KCNH6 protein, this antibody allows for the accurate detection and analysis of KCNH6 expression in a variety of cell types.KCNH6, also known as the Ether-à-go-go homolog 2 (EAG2) channel, plays a crucial role in regulating neuronal excitability and neurotransmitter release.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
KCNH6 Antibody
SKU:
CAB15522
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ERG2, ERG-2, HERG2, Kv11.2, hERG-2, KCNH6
Positive Sample:
293T, HeLa
Cellular Localization:
Membrane, Multi-Pass Membrane Protein.
Calculated MW:
110kDa
Observed MW:
110kDa
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms.
Purification Method
Affinity purification
Gene ID
81033
RRID
AB_2762923
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KCNH6 Rabbit pAb (CAB15522) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
