The [KD Validated] ABCA6 Polyclonal Antibody (CAB21243) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, has been rigorously validated for use in Western blot applications and is highly specific to ABCA6 in human samples.ABCA6 is known for its role in cellular lipid homeostasis and has been implicated in various diseases, including atherosclerosis and neurodegenerative disorders. By targeting ABCA6 with this antibody, researchers can detect and analyze the protein's expression in different cell types, providing valuable insights into its function and potential therapeutic applications.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
[KD Validated] ABCA6 Polyclonal Antibody
SKU:
CAB21243
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
EST155051, [KD Validated] ABCA6
Positive Sample:
293T, RAW264.7, Mouse liver, Rat liver
Cellular Localization:
Membrane, Multi-Pass Membrane Protein.
Calculated MW:
184kDa
Observed MW:
180kDa
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis.
Purification Method
Affinity purification
Gene ID
23460
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using [KD Validated] ABCA6 Rabbit pAb (CAB21243) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Western blot analysis of lysates from wild type(WT) and ABCA6 knockdown (KD) 293T cells, using [KD Validated] ABCA6 Rabbit pAb (CAB21243) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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