The CLIC1 Polyclonal Antibody (CAB10006) is a reliable tool for research involving CLIC1, a protein involved in regulating chloride ion channels and playing a role in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By specifically binding to the CLIC1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an excellent choice for studies in molecular biology, cell physiology, and neuroscience.
CLIC1, also known as chloride intracellular channel protein 1, is a key player in maintaining cellular homeostasis and has been implicated in processes such as cell proliferation, apoptosis, and ion transport. Its diverse functions make it an interesting target for research into diseases like cancer, neurological disorders, and cardiovascular conditions. Investigating the role of CLIC1 can provide valuable insights into disease mechanisms and potential therapeutic strategies aimed at targeting this protein.
Product Name:
[KD Validated] CLIC1 Polyclonal Antibody
SKU:
CAB23677
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 42-241 of human CLIC1(NP_001279.2).
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
Purification Method:
Affinity purification
Gene ID:
1192
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using [KD Validated] CLIC1 Rabbit pAb (CAB23677) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
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