The KDM8 Antibody (CAB11606) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity towards human samples and is optimized for use in Western blot applications. By specifically binding to KDM8, this antibody enables accurate detection and analysis of the protein in various cell types, making it ideal for investigations in the fields of chromatin biology and gene expression regulation.KDM8, a member of the Jumonji C domain-containing histone demethylase family, is crucial for demethylating histone H3 lysine 36 (H3K36) and modulating gene transcription.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
KDM8 Antibody
SKU:
CAB11606
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
JMJD5, KDM8
Positive Sample:
LO2, Mouse eye, Mouse liver
Cellular Localization:
Nucleus.
Calculated MW:
47kDa
Observed MW:
55kDa
This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.
Purification Method
Affinity purification
Gene ID
79831
RRID
AB_2758630
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KDM8 Rabbit pAb (CAB11606) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
