The KIF23 Monoclonal Antibody (CAB4896) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbits, exhibits high specificity for human samples and has been rigorously validated for Western blot applications. By targeting the KIF23 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an invaluable asset for studies in cell biology and cancer research.KIF23, also known as Kinesin-Like Protein 5 (KLP5), is crucial for mitotic spindle formation and chromosome segregation during cell division. Dysregulation of KIF23 has been linked to abnormal cell division and cancer progression, highlighting its potential as a therapeutic target in oncology research.
This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
KIF23 Monoclonal Antibody
SKU:
CAB4896
Size:
20μL, 100μL
Reactivity:
Human, Rat
Clone Number:
ARC0335
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
9493
RRID
AB_2863380
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using KIF23 Rabbit mAb (CAB4896) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Immunoprecipitation analysis of 300 μg extracts of HeLa cells using 3 μg KIF23 Rabbit mAb (CAB4896). Western blot was performed from the immunoprecipitate using KIF23 Rabbit mAb (CAB4896) at a dilution of 1:1000.
