The KLF10 Antibody (CAB13180) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and is suitable for Western blot applications.KLF10, also known as TGF-β-inducible early gene 1, plays a crucial role in mediating the effects of transforming growth factor beta (TGF-β) signaling, impacting gene expression and cellular responses to growth factors and cytokines. Dysregulation of KLF10 has been implicated in diseases such as cancer, fibrosis, and cardiovascular disorders, making it an important target for research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
KLF10 Antibody
SKU:
CAB13180
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
EGRA, TIEG, TIEG1, EGR-alpha, KLF10
Positive Sample:
Mouse kidney, Mouse skeletal muscle, Rat kidney
Cellular Localization:
Nucleus.
Calculated MW:
53kDa
Observed MW:
56kDa
This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
7071
RRID
AB_2760031
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLF10 Rabbit pAb (CAB13180) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
