The KLF7 Polyclonal Antibody (CAB8879) is a valuable tool for researchers studying the Krüppel-like factor 7 (KLF7) protein, a transcription factor involved in various cellular processes such as cell proliferation, differentiation, and apoptosis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.KLF7, a member of the KLF family of transcription factors, plays a key role in the regulation of gene expression and is implicated in a wide range of biological functions, including development, metabolism, and neurogenesis.
Its dysregulation has been associated with various diseases, making it a promising target for therapeutic interventions.By using the KLF7 Polyclonal Antibody, researchers can detect and analyze KLF7 protein levels in different cell types, allowing for a better understanding of its function in normal physiology and disease states. This antibody is a valuable resource for studies in molecular biology, cell biology, and developmental biology, providing insights into the intricate mechanisms underlying cellular processes regulated by KLF7.
Product Name:
KLF7 Rabbit Polyclonal Antibody
SKU:
CAB8879
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 51-230 of human KLF7 (NP_001257871.1).
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8609
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Mouse kidney, using KLF7 antibody (CAB8879) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
