The KLHL41 Polyclonal Antibody (CAB15383) is a valuable tool for research involving KLHL41, a protein involved in cellular processes such as protein degradation and cytoskeleton organization. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for various experimental applications including Western blotting.KLHL41 is a member of the Kelch-like family of proteins and is known to interact with Cullin-3, a component of the E3 ubiquitin ligase complex. This interaction plays a crucial role in regulating protein turnover and maintaining cellular homeostasis.
Research on KLHL41 is important for understanding its function in cellular processes and its potential implications in diseases such as cancer and neurological disorders.The KLHL41 Polyclonal Antibody allows for the detection and analysis of KLHL41 protein levels in different cell types, enabling researchers to further investigate its role in cellular pathways. By studying KLHL41, scientists can gain insights into potential therapeutic targets for diseases associated with dysregulation of protein degradation pathways.
Product Name:
KLHL41 Rabbit Polyclonal Antibody
SKU:
CAB15383
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KLHL41 (NP_006054.2).
This gene is a member of the kelch-like family. The encoded protein contains a BACK domain, a BTB/POZ domain, and 5 Kelch repeats. This protein is thought to function in skeletal muscle development and maintenance. Mutations in this gene have been associated with nemaline myopathy (NM), a rare congenital muscle disorder.
Purification Method:
Affinity purification
Gene ID:
10324
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLHL41 Rabbit pAb (CAB15383) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
