The KRT79 Polyclonal Antibody (PAC036426) is a valuable tool for researchers studying the keratin 79 protein, which plays a key role in hair development and maintenance. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various experimental applications, including Western blotting.Keratin 79 is primarily expressed in hair follicles and is involved in the structural integrity of hair fibers. By targeting the KRT79 protein, researchers can investigate the mechanisms underlying hair growth and differentiation, as well as potential therapeutic interventions for hair disorders.
The KRT79 Polyclonal Antibody enables specific detection and analysis of KRT79 in different cell types, making it a versatile tool for studies in dermatology, regenerative medicine, and cosmetic science. Understanding the function of KRT79 can provide insights into hair biology and offer opportunities for developing innovative treatments for hair-related conditions.
Antibody Name:
KRT79 Antibody (PACO36426)
Antibody SKU:
PACO36426
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant Human Keratin, type II cytoskeletal 79 protein (1-300AA)
Western blot. All lanes: KRT79 antibody at 1µg/ml. Lane 1: Mouse lung tissue. Lane 2: A549 whole cell lysate. Lane 3: 293T whole cell lysate. Lane 4: Mouse gonadal tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 58 kDa. Observed band size: 58 kDa.
Background:
There are two types of cytoskeletal and microfibrillar keratin, I (acid, c) and II (neutral to basic) (40-55 and 56-70 kDa, respectively).
Synonyms:
Keratin, type II cytoskeletal 79 (Cytokeratin-79) (CK-79) (Keratin-6-like) (Keratin-6L) (Keratin-79) (K79) (Type-II keratin Kb38), KRT79, K6L KB38 KRT6L
UniProt Protein Function:
KRT79: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in skeletal muscle, skin and scalp. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]Protein type: CytoskeletalChromosomal Location of Human Ortholog: 12q13.13Molecular Function: enzyme binding; protein binding
UniProt Protein Details:
NCBI Summary:
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in skeletal muscle, skin and scalp. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]
