The LAMP1 Polyclonal Antibody (CAB23253) is a crucial tool for researchers studying lysosomal-associated membrane protein 1 (LAMP1), a key player in lysosomal biogenesis and function. This antibody, generated in rabbits, demonstrates high specificity and sensitivity for detecting LAMP1 in various biological samples, particularly in Western blotting applications.LAMP1 is involved in maintaining lysosomal integrity, regulating lysosomal pH, and facilitating lysosomal fusion with other organelles.
Dysregulation of LAMP1 expression or function has been implicated in various diseases, including lysosomal storage disorders, neurodegenerative diseases, and cancer. By using the LAMP1 Polyclonal Antibody, researchers can investigate the role of LAMP1 in these pathological conditions and explore potential therapeutic targets related to lysosomal dysfunction.
Product Name:
LAMP1 Polyclonal Antibody
SKU:
CAB23253
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 208-363 of mouse LAMP1 (NP_001304282.1).
Enables protein domain specific binding activity. Involved in protein stabilization. Located in several cellular components, including cytoplasmic vesicle; sarcolemma; and vacuole. Is expressed in several structures, including 1-cell stage embryo; central nervous system; craniocervical region bone; extraembryonic component; and gut. Orthologous to human LAMP1 (lysosomal associated membrane protein 1).
Purification Method:
Affinity purification
Gene ID:
16783
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LAMP1 Rabbit pAb (CAB23253) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
