The LAMP1 Antibody (CAB2582) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is produced in rabbits and has been validated for use in Western blot applications, providing reliable detection and analysis of LAMP1 in various cell types.LAMP1 is essential for the functioning of lysosomes and autophagosomes, playing a critical role in cellular processes such as protein degradation, lipid metabolism, and antigen presentation. Dysregulation of LAMP1 is implicated in various diseases, including cancer, neurodegenerative disorders, and lysosomal storage diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
LAMP1 Antibody
SKU:
CAB2582
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
LAMPA, CD107a, LGP120, LAMP1
Positive Sample:
U-937, HeLa
Cellular Localization:
Cell Membrane, Endosome Membrane, Late Endosome, Lysosome Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
45kDa
Observed MW:
90-120kDa
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.
Purification Method
Affinity purification
Gene ID
3916
RRID
AB_2764468
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from U-937 cells, using LAMP1 Rabbit pAb (CAB2582) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Western blot analysis of lysates from wild type(WT) and LAMP1 knockout (KO) HeLa cells, using LAMP1 Rabbit pAb (CAB2582) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
