The LARP7 Antibody (CAB13095) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for LARP7 and has been validated for use in various applications, including Western blot and immunohistochemistry.LARP7, also known as La-related protein 7, plays a critical role in maintaining proper RNA stability and processing, particularly in the context of ribosome biogenesis and mRNA splicing. Dysregulation of LARP7 has been implicated in various diseases, including cancer and developmental disorders, making it an important target for further investigation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
LARP7 Antibody
SKU:
CAB13095
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ALAZS, PIP7S, hLARP7, HDCMA18P, LARP7
Positive Sample:
U-87MG, Jurkat, Mouse testis
Cellular Localization:
Nucleus, Nucleoplasm.
Calculated MW:
67kDa
Observed MW:
71kDa
This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
51574
RRID
AB_2759944
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LARP7 Rabbit pAb (CAB13095) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
