The LC3B Polyclonal Antibody (CAB11923) is a powerful tool for conducting research on autophagy, a cellular process crucial for maintaining cellular homeostasis and regulating various cellular functions. This antibody, generated in rabbits, shows high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications.LC3B, a key protein in the autophagy process, is involved in the formation of autophagosomes, the double-membrane vesicles responsible for engulfing cellular components for degradation. Studying the expression and localization of LC3B can provide valuable insights into autophagy-related pathways, making this antibody indispensable for researchers interested in studying autophagy, cellular stress responses, and disease mechanisms.
With its ability to specifically target and detect the LC3B protein in various cell types, the CAB11923 antibody holds great promise for advancing research in areas such as cancer biology, neurodegenerative diseases, and metabolic disorders. By understanding the role of LC3B in autophagy, researchers can uncover new therapeutic targets and develop innovative treatments for diseases associated with disrupted autophagy pathways.
Product Name:
LC3B Polyclonal Antibody
SKU:
CAB11923
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LC3B (NP_073729.1).
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
Purification Method:
Affinity purification
Gene ID:
81631
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from 293 cells, using LC3B Rabbit pAb (CAB11923).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
