The LDLRAD3 Polyclonal Antibody (PACO22394) is a valuable tool for researchers studying LDLRAD3, a key protein involved in lipid metabolism and cardiovascular health. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically recognizing and binding to LDLRAD3, this antibody enables precise detection and analysis in a variety of cell types.LDLRAD3, also known as C2 laminin domain-containing protein, plays a crucial role in regulating LDL receptor levels and cholesterol homeostasis. Dysregulation of LDLRAD3 has been implicated in cardiovascular diseases such as atherosclerosis and hypercholesterolemia.
Research into the function and mechanism of LDLRAD3 is essential for developing novel therapeutic strategies for managing lipid-related disorders.Whether investigating the role of LDLRAD3 in cardiovascular health or exploring its potential as a therapeutic target, the LDLRAD3 Polyclonal Antibody is a valuable resource for researchers in fields such as cardiology, lipid biology, and drug discovery. Its high specificity and sensitivity make it an excellent tool for furthering our understanding of LDLRAD3 and its implications in human health.
Antibody Name:
LDLRAD3 Antibody (PACO22394)
Antibody SKU:
PACO22394
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:100-1:500
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human LDLRAD3.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunofluorescence analysis of A549 cells, using LDLRAD3 antibody.
Background:
May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production By similarity.
Synonyms:
Low-density lipoprotein receptor class A domain-containing protein 3;
UniProt Protein Function:
LDLRAD3: May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. Belongs to the LDLR family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 11p13Cellular Component: cell junction
