The LILRA5 Polyclonal Antibody (PACO02140) is a valuable tool for researchers studying LILRA5, a member of the leukocyte immunoglobulin-like receptor (LILR) family involved in immune regulation. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the LILRA5 protein, this antibody enables researchers to analyze and detect LILRA5 expression in various cell types, making it ideal for immunology and cancer research studies.
LILRA5 is known to play a role in modulating immune responses, making it a key molecule in the regulation of inflammation and immune cell activation. Its involvement in immune system homeostasis highlights its relevance in understanding diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By studying the function of LILRA5, researchers can gain insights into developing targeted therapies that manipulate immune responses to combat these diseases effectively.
Antibody Name:
LILRA5 Antibody
Antibody SKU:
PACO02140
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human CD85f.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
LILRA5; ILT11; LILRB7; LIR9; Leukocyte immunoglobulin-like receptor subfamily A member 5; CD85 antigen-like family member F; Immunoglobulin-like transcript 11; ILT-11; Leukocyte immunoglobulin-like receptor 9; LIR-9; CD85f
UniProt Protein Function:
LILRA5: May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition. 4 isoforms of the human protein are produced by alternative splicingChromosomal Location of Human Ortholog: 19q13.4
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
