The Rhombotin-1 Polyclonal Antibody (CAB7561) is a valuable tool for researchers studying the Rhombotin-1 protein, a transcription factor involved in hematopoiesis and leukemia. This antibody, raised in rabbits, exhibits high specificity and sensitivity for human samples, making it an ideal choice for Western blot applications.Rhombotin-1 is known to play a critical role in regulating gene expression in hematopoietic cells, making it a key target for research in leukemia and other blood disorders. By specifically targeting the Rhombotin-1 protein, this antibody enables accurate detection and analysis in various cell types, providing valuable insights into its function and potential therapeutic applications.
Furthermore, understanding the role of Rhombotin-1 in hematopoiesis and leukemia development is essential for developing targeted therapies that may improve treatment outcomes for patients battling these diseases. The Rhombotin-1 Polyclonal Antibody (CAB7561) offers researchers a reliable tool to further explore the mechanisms underlying these conditions and advance our understanding of their molecular pathways.
Product Name:
LMO1 Rabbit Polyclonal Antibody
SKU:
CAB7561
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-156 of human LMO1 (NP_002306.1).
This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
4004
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of U-251MG cells, using LMO1 antibody (CAB7561) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
