The LNX1 Antibody (CAB6481) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human LNX1 and has been validated for use in Western blot applications.LNX1 is known to interact with multiple proteins in the cell, playing a role in regulating pathways related to cell growth, differentiation, and survival. By targeting LNX1, researchers can gain insights into the mechanisms underlying these processes and investigate its potential as a therapeutic target in diseases such as cancer and neurological disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
LNX1 Antibody
SKU:
CAB6481
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
LNX, MPDZ, PDZRN2, LNX1
Positive Sample:
293F, MCF7, Mouse heart, Mouse brain, Rat brain, Rat heart
Cellular Localization:
Cytoplasm.
Calculated MW:
81kDa
Observed MW:
75kDa
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.
Purification Method
Affinity purification
Gene ID
84708
RRID
AB_2767082
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using LNX1 Rabbit pAb (CAB6481) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
