The LPAR2 Antibody (CAB14819) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for studying LPAR2 expression and function in cell biology and pharmacology research.LPAR2, a member of the lysophospholipid receptor family, is involved in signal transduction pathways that regulate cell growth and survival. Its activation by lysophosphatidic acid (LPA) leads to downstream signaling events that can impact cellular processes such as cell adhesion, cytoskeletal rearrangement, and gene expression.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
LPAR2 Antibody
SKU:
CAB14819
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined.
Purification Method
Affinity purification
Gene ID
9170
RRID
AB_2761697
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HL-60 cells, using LPAR2 Rabbit pAb (CAB14819) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
