The LRP3 Polyclonal Antibody (PACO22397) is a valuable tool for researchers studying LRP3, a key protein involved in various cellular processes including lipid metabolism, inflammation, and immune response. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.LRP3, also known as the low-density lipoprotein receptor-related protein 3, is a crucial regulator of cholesterol homeostasis and has been implicated in the development of metabolic disorders such as atherosclerosis and cardiovascular diseases.
Additionally, LRP3 has been shown to play a role in immune responses, suggesting its potential as a therapeutic target for conditions like autoimmune diseases and inflammatory disorders.By enabling the detection and analysis of LRP3 in different cell types, the PACO22397 antibody is an essential tool for researchers looking to further understand the biological functions of this protein. Its high reactivity and specificity make it an ideal choice for studies in the fields of lipid metabolism, inflammation, and immunology.
Antibody Name:
LRP3 Antibody (PACO22397)
Antibody SKU:
PACO22397
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human LRP3.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from RAW264.7 cells, using LRP3 antibody.
Background:
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
Synonyms:
low-density lipoprotein receptor-related protein 3; LRp105;
UniProt Protein Function:
LRP3: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro. Belongs to the LDLR family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.11Biological Process: receptor-mediated endocytosis
