The LRRC57 Antibody (PAC016632) is a polyclonal antibody designed for research involving LRRC57, a protein involved in cellular processes and signaling pathways. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blot and immunofluorescence.LRRC57, also known as Leucine-Rich Repeat Containing 57, has been implicated in cellular functions related to protein-protein interactions and signal transduction. Studies have shown its involvement in cell cycle regulation, DNA repair mechanisms, and intracellular signaling cascades. The LRRC57 antibody binds specifically to the LRRC57 protein, allowing for its detection and analysis in different cell types and tissues.
The role of LRRC57 in cellular processes and its potential implications in disease development make it a valuable target for further research. By studying the function and regulation of LRRC57, researchers can gain insights into various biological processes and potentially uncover new therapeutic targets for diseases such as cancer, neurodegenerative disorders, and metabolic conditions. This antibody is a valuable tool for scientists conducting research in cell biology, molecular biology, and biomedical sciences.
Antibody Name:
LRRC57 Antibody (PACO16632)
Antibody SKU:
PACO16632
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human LRRC57
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO16632(LRRC57 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16632(LRRC57 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
LRRC57 (leucine rich repeat containing 57) is a 239 amino acid, protein that contains eight LRR repeats and is encoded by a gene that maps to human chromosome 15q15.2. Chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
Synonyms:
leucine rich repeat containing 57
UniProt Protein Function:
LRRC57: Chromosomal Location of Human Ortholog: 15q15.2
