The LRRK2 Monoclonal Antibody (CAB22759) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using hybridoma technology, shows high specificity and sensitivity in detecting LRRK2 in human samples, making it ideal for use in Western blot and immunohistochemistry applications.LRRK2, a multidomain protein kinase, is involved in various cellular processes, including autophagy, inflammation, and neuronal survival.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
LRRK2 Monoclonal Antibody
SKU:
CAB22759
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC55202
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:100 - 1:500
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Purification Method
Affinity purification
Gene ID
120892
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using LRRK2 Rabbit mAb (CAB22759) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Negative control (NC): U-937. Exposure time: 180 s.
