Description
LXN Antibody (PACO01848)
The LXN Antibody (PAC001848) is a valuable tool for researchers studying LXN, a protein with tumor suppressor properties. This polyclonal antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to LXN, this antibody facilitates the detection and analysis of LXN expression in various cell types, making it ideal for investigations in oncology and cancer biology.LXN, also known as Latexin, is involved in the regulation of cell proliferation and differentiation, and its dysregulation has been linked to tumorigenesis in various cancers.
Understanding the molecular mechanisms underlying LXN function is crucial for developing targeted therapies for cancer treatment. By using the LXN Antibody, researchers can gain insights into the role of LXN in tumor development and progression, paving the way for the development of novel therapeutic strategies.
| Antibody Name: | LXN Antibody |
| Antibody SKU: | PACO01848 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human Latexin. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | LXN; Latexin; Endogenous carboxypeptidase inhibitor; ECI; Protein MUM; Tissue carboxypeptidase inhibitor; TCI |
| UniProt Protein Function: | LXN: Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. Belongs to the protease inhibitor I47 (latexin) family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3q25.32 Molecular Function:protein binding |
| NCBI Summary: | This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. [provided by RefSeq, Oct 2008] |
| UniProt Code: | Q9BS40 |
| NCBI GenInfo Identifier: | 146345452 |
| NCBI Gene ID: | 56925 |
| NCBI Accession: | Q9BS40.2 |
| UniProt Secondary Accession: | Q9BS40,Q96PN2, Q9NQS6, |
| UniProt Related Accession: | Q9BS40 |
| Molecular Weight: | 25,750 Da |
| NCBI Full Name: | Latexin |
| NCBI Synonym Full Names: | latexin |
| NCBI Official Symbol: | LXNÂ Â |
| NCBI Official Synonym Symbols: | ECI; TCIÂ Â |
| NCBI Protein Information: | latexin |
| UniProt Protein Name: | Latexin |
| UniProt Synonym Protein Names: | Endogenous carboxypeptidase inhibitor; ECI; Protein MUM; Tissue carboxypeptidase inhibitor; TCI |
| Protein Family: | Latexin |
| UniProt Gene Name: | LXNÂ Â |
| UniProt Entry Name: | LXN_HUMAN |
