The MAGEA5 Antibody (PAC028110) is a highly specific tool for studying the MAGEA5 protein, a cancer/testis antigen involved in tumorigenesis and tumor progression. This antibody, produced in rabbits, has been validated for use in various research applications, particularly Western blot analysis. By targeting the MAGEA5 protein, researchers can easily detect and quantify its presence in cancer cells, aiding in the development of targeted therapies for cancer treatment.MAGEA5 is known to be overexpressed in a variety of cancer types, making it a promising target for cancer immunotherapy and personalized medicine.
By understanding the role of MAGEA5 in promoting tumor growth and metastasis, researchers can identify new strategies for combating cancer and improving patient outcomes. The MAGEA5 Antibody is a valuable tool for advancing our knowledge of cancer biology and developing more effective treatment options for patients with MAGEA5-positive tumors.
Antibody Name:
MAGEA5 Antibody (PACO28110)
Antibody SKU:
PACO28110
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Melanoma-associated antigen 5 protein (1-124AA)
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene. [provided by RefSeq, Oct 2011]
