The MAGEA6 Polyclonal Antibody (CAB8130) is a valuable tool for researchers studying MAGEA6, a cancer/testis antigen involved in tumorigenesis and cancer progression. This antibody, generated in rabbits, is highly specific to human MAGEA6 and has been validated for use in various applications, including Western blot and immunohistochemistry.MAGEA6 is known to play a critical role in promoting tumor growth and metastasis, making it an attractive target for cancer research and potential therapeutic interventions. The MAGEA6 Polyclonal Antibody enables the detection and analysis of MAGEA6 expression in cancer cell lines and tissues, providing valuable insights into its function and potential as a biomarker for cancer diagnosis and prognosis.
Overall, the MAGEA6 Polyclonal Antibody is a reliable tool for researchers investigating the role of MAGEA6 in cancer biology, with the potential to advance our understanding of tumor development and progression, as well as the development of targeted therapies for MAGEA6-expressing cancers.
Product Name:
MAGEA6 Rabbit Polyclonal Antibody
SKU:
CAB8130
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 75-314 of human MAGEA6 (NP_005354.1).
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4105
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAGEA6 antibody (CAB8130) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
