The MAGE-A9 Polyclonal Antibody (PAC004275) is a crucial tool for researchers studying MAGE-A9, a member of the MAGE family of cancer-testis antigens frequently overexpressed in various malignancies. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human MAGE-A9 protein, making it suitable for Western blot analysis.MAGE-A9 is of interest in cancer research due to its aberrant expression in tumors, presenting it as a potential target for immunotherapy and targeted therapy. By targeting MAGE-A9, researchers aim to develop novel treatment strategies for cancer patients, particularly those with MAGE-A9-positive tumors. The MAGE-A9 Polyclonal Antibody enables precise detection and quantification of MAGE-A9 protein levels in cancer cell lines and tissues, facilitating in-depth investigations into its role in oncogenesis and potential therapeutic applications.
With its ability to accurately detect MAGE-A9 in experimental settings, this antibody is a valuable tool for researchers seeking to unravel the molecular mechanisms underlying cancer development and progression. By elucidating the functions of MAGE-A9, scientists can pave the way for innovative approaches to cancer treatment and personalized medicine strategies tailored to target specific tumor antigens like MAGE-A9.
Antibody Name:
MAGEA9 Antibody
Antibody SKU:
PACO04275
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human MAGE-9.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
MAGE-A9: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xq28
UniProt Protein Details:
NCBI Summary:
MAGEA9B is a duplication of the MAGEA9 gene (MIM 300342) on chromosome Xq28. The 2 copies are separated by about 194 kb (Hartz, 2009).[supplied by OMIM, Mar 2009]
