The MAGEB18 Polyclonal Antibody (PACO39874) is a valuable tool for researchers studying MAGEB18, a member of the MAGE superfamily that is involved in cancer development and progression. This antibody, produced in rabbits, is highly specific for detecting MAGEB18 in human samples and is validated for use in Western blot applications. By binding to the MAGEB18 protein, this antibody enables researchers to analyze its expression in various cell types, making it a valuable asset for studies in cancer biology and tumor immunology.MAGEB18, a cancer-testis antigen, is known to play a role in tumorigenesis and is frequently overexpressed in various cancer types.
Its involvement in promoting tumor growth and metastasis makes it an attractive target for research aimed at developing targeted cancer therapies. By elucidating the mechanisms underlying MAGEB18-mediated oncogenesis, researchers can gain valuable insights into novel therapeutic approaches for combating cancer.Overall, the MAGEB18 Polyclonal Antibody is a key tool for researchers investigating the role of MAGEB18 in cancer biology and immunotherapy. Its high specificity and sensitivity make it an ideal choice for detecting and studying MAGEB18 expression, ultimately contributing to advancements in the field of cancer research.
Antibody Name:
MAGEB18 Antibody (PACO39874)
Antibody SKU:
PACO39874
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant Human Melanoma-associated antigen B18 protein (1-270AA)
Western blot. All lanes: MAGEB18 antibody at 12µg/ml. Lane 1: MCF-7 whole cell lysate. Lane 2: A549 whole cell lysate. Lane 3: Hela whole cell lysate. Lane 4: Mouse heart tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 39 kDa. Observed band size: 39 kDa.
Background:
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
