The Magee1 Monoclonal Antibody (PAC019976) is a valuable tool for researchers studying Magee1, a protein involved in immune regulation and inflammatory responses. This antibody, produced using hybridoma technology, is highly specific to Magee1 and has been validated for use in various applications, including immunofluorescence and flow cytometry.Magee1, also known as a potential immune modulator, plays a crucial role in regulating immune cell function and inflammatory processes. By targeting Magee1, researchers can gain valuable insights into the mechanisms underlying immune dysregulation in various diseases, such as autoimmune disorders, inflammatory conditions, and cancer.
This monoclonal antibody provides researchers with a reliable tool for detecting and quantifying Magee1 in different cell types and tissues, making it an ideal choice for studies in immunology and cancer research. With its high specificity and sensitivity, the Magee1 Monoclonal Antibody is a valuable asset for researchers seeking to unravel the complexities of immune modulation and inflammatory pathways.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19976(MAGEE1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: PACO19976(MAGEE1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19976(MAGEE1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid, repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation.
