The MAP3K11 Antibody (CAB16242) is a high-quality antibody developed for reliable detection and analysis of target proteins. The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. RRID AB_2770265 Gene ID 4296 Swiss Prot Synonym MLK3; PTK1; SPRK; MLK-3; MEKK11; MAP3K11
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
MAP3K11 Antibody
SKU:
CAB16242
Size:
100μL, 20μL
Reactivity:
Mouse
Clone Number:
-
Conjugate:
-
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MLK3, PTK1, SPRK, MLK-3, MEKK11, MAP3K11
Positive Sample:
Mouse thymus
Cellular Localization:
Centrosome, Cytosol.
Calculated MW:
93kDa
Observed MW:
93kDa
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. RRID AB_2770265 Gene ID 4296 Swiss Prot Synonym MLK3; PTK1; SPRK; MLK-3; MEKK11; MAP3K11
Purification Method:
Affinity purification
Gene ID:
4296
RRID:
AB_2770265
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse thymus, using MAP3K11 Rabbit pAb (CAB16242) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
