Description
MAST4 Antibody (PACO05968)
The MAST4 Antibody (PACO05968) is a polyclonal antibody specifically designed for research involving MAST4, a protein kinase that plays a key role in cell division and cell migration processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the MAST4 protein, researchers can detect and analyze its expression in various cell types, providing valuable insights into its function in cellular dynamics.MAST4 is known to be involved in regulating microtubule dynamics and cell shape changes during cell division and migration.
Its importance in these processes makes it a promising target for studies in cell biology, cancer research, and developmental biology. By understanding the role of MAST4 in these contexts, researchers can uncover potential therapeutic targets for diseases like cancer, where aberrant cell division and migration are key factors in disease progression.Overall, the MAST4 Antibody (PACO05968) serves as a valuable tool for investigating the functions of MAST4 in various cellular processes, providing crucial insights for advancing our understanding of cell biology and disease mechanisms.
| Antibody Name: | MAST4 Antibody (PACO05968) |
| Antibody SKU: | PACO05968 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:5000, WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from the N-terminal region of human MAST4. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | MAST4; KIAA0303; Microtubule-associated serine/threonine-protein kinase 4 |
| UniProt Protein Function: | MAST4: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; Protein kinase, AGC; AGC group; MAST family Chromosomal Location of Human Ortholog: 5q12.3 Cellular Component: cytoplasm Molecular Function:protein serine/threonine kinase activity; magnesium ion binding; ATP binding Biological Process: protein amino acid phosphorylation |
| NCBI Summary: | This gene encodes a member of the microtubule-associated serine/threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014] |
| UniProt Code: | O15021 |
| NCBI GenInfo Identifier: | 589811546 |
| NCBI Gene ID: | 375449 |
| NCBI Accession: | NP_001277155.1 |
| UniProt Secondary Accession: | O15021,Q05EE6, Q6ZN07, Q8N4X4, Q96LY3, A6NL49, B5ME48 |
| UniProt Related Accession: | O15021 |
| Molecular Weight: | |
| NCBI Full Name: | microtubule-associated serine/threonine-protein kinase 4 isoform d |
| NCBI Synonym Full Names: | microtubule associated serine/threonine kinase family member 4 |
| NCBI Official Symbol: | MAST4Â Â |
| NCBI Protein Information: | microtubule-associated serine/threonine-protein kinase 4 |
| UniProt Protein Name: | Microtubule-associated serine/threonine-protein kinase 4 |
| Protein Family: | Microtubule-associated serine/threonine-protein kinase |
| UniProt Gene Name: | MAST4Â Â |
| UniProt Entry Name: | MAST4_HUMAN |
