The MEOX2 Polyclonal Antibody (PAC021789) is a valuable tool for researchers studying the MEOX2 protein, which is involved in various biological processes such as development, differentiation, and tissue homeostasis. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an excellent choice for Western blot and immunofluorescence applications.MEOX2, also known as GAX, is a transcription factor that plays a crucial role in regulating gene expression and cell fate determination.
Its dysregulation has been implicated in diseases such as cancer, cardiovascular disorders, and developmental abnormalities. By targeting MEOX2 with this antibody, researchers can explore its functions in different cell types and elucidate its role in disease pathogenesis.Overall, the MEOX2 Polyclonal Antibody is a reliable tool for investigating the molecular mechanisms underlying MEOX2 function, paving the way for new therapeutic strategies in various fields, including oncology and regenerative medicine.
Antibody Name:
MEOX2 Antibody (PACO21789)
Antibody SKU:
PACO21789
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human MEOX2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from COLO205 cells, using MEOX2 antibody.
Background:
Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle By similarity. Lepage D.F., Genomics 24:535-540(1994).
Synonyms:
Mesenchyme homeobox 2;
UniProt Protein Function:
MEOX2: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
UniProt Protein Details:
Protein type:DNA-binding
Chromosomal Location of Human Ortholog: 7p22.1-p21.3
Cellular Component: cytoplasm; nucleus
Molecular Function:protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: blood circulation; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter
NCBI Summary:
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008]
