The MIER2 Polyclonal Antibody (PAC016689) is a valuable tool for researchers studying MIER2, a transcriptional regulator involved in gene expression and cell development. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications. By targeting the MIER2 protein, this antibody enables the detection and analysis of MIER2 expression in various cell types, making it an excellent choice for studies in molecular biology and developmental biology.MIER2, also known as mesoderm induction early response 1 family member 2, plays a crucial role in regulating gene expression and cell differentiation processes.
Its involvement in these fundamental cellular processes makes it a key target for research in fields such as embryology, stem cell biology, and cancer biology. Understanding the function of MIER2 is essential for unraveling the mechanisms underlying cellular development and disease progression, providing insights that could lead to novel therapeutic strategies in the future.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16689(MIER2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: PACO16689(MIER2 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16689(MIER2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
Background:
MIER2(mesoderm induction early response 1, family member 2), also known as Mi-er2 or KIAA1193, is a protein that in humans is encoded by the MIER2 gene. It is a transcriptional repressor.
Synonyms:
mesoderm induction early response 1, family member 2
UniProt Protein Function:
MIER2: Transcriptional repressor.
UniProt Protein Details:
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleus
Molecular Function:DNA binding; chromatin binding
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
