The MIER2 Polyclonal Antibody (PAC037918) is a key tool for researchers studying MIER2, a transcriptional regulator with important roles in gene expression and cell growth. This antibody, produced in rabbits, has high specificity for human samples and is validated for use in Western blot applications. By binding to the MIER2 protein, this antibody enables researchers to detect and analyze MIER2 expression in various cell types, making it essential for studies in molecular biology and cancer research.
MIER2, also known as mesoderm induction early response 1, plays a crucial role in regulating gene transcription and influencing cellular processes such as proliferation and differentiation. Its involvement in these fundamental cellular functions highlights its importance as a target for research into diseases like cancer and developmental disorders. Understanding the function of MIER2 is essential for uncovering its potential as a therapeutic target for various medical conditions.
Western blot. All lanes: MIER2 antibody at 4µg/ml. Lane 1: Jurkat whole cell lysate. Lane 2: HepG2 whole cell lysate. Lane 3: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 60 kDa. Observed band size: 60 kDa.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO37918 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver tissue using PACO37918 at dilution of 1:100.
Background:
Transcriptional repressor.
Synonyms:
Mesoderm induction early response protein 2 (Mi-er2), MIER2, KIAA1193
UniProt Protein Function:
MIER2: Transcriptional repressor.
UniProt Protein Details:
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleus
Molecular Function:DNA binding; chromatin binding
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
