The MFN1 Antibody (CAB9880) is a high-quality antibody developed for reliable detection and analysis of target proteins. Mitofusin-1 is a protein involved in mitochondrial fusion, a process essential for maintaining mitochondrial health and proper cellular function. This antibody, generated in rabbits, specifically recognizes Mitofusin-1 in human samples and is validated for use in Western blot applications.By targeting Mitofusin-1, researchers can investigate the role of mitochondrial fusion in various cellular processes, including energy production, apoptosis regulation, and cellular signaling. Dysregulation of mitochondrial dynamics has been linked to a range of human diseases, making Mitofusin-1 an important target for studies in areas such as neurodegeneration, metabolic disorders, and cancer.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
MFN1 Antibody
SKU:
CAB9880
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
Purification Method
Affinity purification
Gene ID
55669
RRID
AB_2770351
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using Mitofusin-1/MFN1 Rabbit pAb (CAB9880) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Western blot analysis of lysates from Rat heart, using Mitofusin-1/MFN1 Rabbit pAb (CAB9880) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
