The MORC2 Polyclonal Antibody (CAB17641) is a valuable tool for researchers studying the MORC2 protein, a key player in chromatin remodeling and gene regulation. This rabbit polyclonal antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to the MORC2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and epigenetics.MORC2, also known as Microrchidia 2, is involved in maintaining genome stability and regulating gene expression by modifying chromatin structure.
Dysregulation of MORC2 has been implicated in various diseases, including cancer and neurodevelopmental disorders. Understanding the function of MORC2 is essential for uncovering its role in disease processes and developing targeted therapies.Overall, the MORC2 Polyclonal Antibody (CAB17641) offers researchers a reliable tool for investigating the function and implications of MORC2 in various biological processes, paving the way for advancements in biomedical research and potential therapeutic interventions.
Product Name:
MORC2 Rabbit Polyclonal Antibody
SKU:
CAB17641
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-250 of human MORC2 (NP_055756.1).
This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
22880
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MORC2 Rabbit pAb (CAB17641) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
